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Thermally inactivated simian virus 40 tsA58 mutant T antigen cannot initiate viral DNA replication in vitro.
The mutation in the temperature-sensitive tsA58 mutant T antigen (Ala-438----Val) lies within the presumptive ATP-binding fold. We have constructed a recombinant baculovirus that expresses large quantities of the tsA58 T antigen in infected insect cells. The mutant T antigen mediated simian virus 40...
Shranjeno v:
| izdano v: | J Virol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1990
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2173789/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.12.6234-6245.1990 |
| Oznake: |
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