Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination.

Infection with human cytomegalovirus in the presence of the antiviral nucleotide analog ganciclovir results in continuing low-level viral DNA synthesis and the accumulation of relatively small fragments of double-stranded progency DNA. These fragments consistently proved to represent amplification o...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hamzeh, F M, Lietman, P S, Gibson, W, Hayward, G S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2173786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.12.6184-6195.1990
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