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Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination.

Infection with human cytomegalovirus in the presence of the antiviral nucleotide analog ganciclovir results in continuing low-level viral DNA synthesis and the accumulation of relatively small fragments of double-stranded progency DNA. These fragments consistently proved to represent amplification o...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Hamzeh, F M, Lietman, P S, Gibson, W, Hayward, G S
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1990
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2173786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.12.6184-6195.1990
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