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Mechanism of antigenic variation in an individual epitope on influenza virus N9 neuraminidase.

Monoclonal antibodies which inhibit influenza virus neuraminidase (NA) and which therefore indirectly neutralize virus infectivity bind to epitopes located on the rim of the active-site crater. The three-dimensional structure of one of these epitopes, recognized by monoclonal antibody NC41, has prev...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Air, G M, Laver, W G, Webster, R G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC248733/
https://ncbi.nlm.nih.gov/pubmed/1700825
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