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Trifluoromethyl ethers – synthesis and properties of an unusual substituent

After nitrogen, fluorine is probably the next most favorite hetero-atom for incorporation into small molecules in life science-oriented research. This review focuses on a particular fluorinated substituent, the trifluoromethoxy group, which is finding increased utility as a substituent in bioactives...

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Main Authors: Leroux, Frédéric R, Manteau, Baptiste, Vors, Jean-Pierre, Pazenok, Sergiy
格式: Artigo
語言:Inglês
出版: Beilstein-Institut 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486484/
https://ncbi.nlm.nih.gov/pubmed/18941485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.4.13
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