Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme

CCA-adding enzyme builds the 3′-end CCA of tRNA without a nucleic acid template. The mechanism for the maintenance of fidelity during the CCA-adding reaction remains elusive. Here, we present almost a dozen complex structures of the class I CCA-adding enzyme and tRNA mini-helices (mini-D(73)N(74), m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Toh, Yukimatsu, Numata, Tomoyuki, Watanabe, Kazunori, Takeshita, Daijiro, Nureki, Osamu, Tomita, Kozo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486279/
https://ncbi.nlm.nih.gov/pubmed/18583961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.124
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