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Mechanism for the definition of elongation and termination by the class II CCA-adding enzyme

The CCA-adding enzyme synthesizes the CCA sequence at the 3′ end of tRNA without a nucleic acid template. The crystal structures of class II Thermotoga maritima CCA-adding enzyme and its complexes with CTP or ATP were determined. The structure-based replacement of both the catalytic heads and nucleo...

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Detalhes bibliográficos
Main Authors: Toh, Yukimatsu, Takeshita, Daijiro, Numata, Tomoyuki, Fukai, Shuya, Nureki, Osamu, Tomita, Kozo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776095/
https://ncbi.nlm.nih.gov/pubmed/19745807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.260
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