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Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization

The function of the Ets-1 transcription factor is regulated by two regions that flank its DNA-binding domain. A previously established mechanism for auto-inhibition of monomeric Ets-1 on DNA response elements with a single ETS-binding site, however, has not been observed for the stromelysin-1 promot...

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Detalhes bibliográficos
Main Authors: Lamber, Ekaterina P, Vanhille, Laurent, Textor, Larissa C, Kachalova, Galina S, Sieweke, Michael H, Wilmanns, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486274/
https://ncbi.nlm.nih.gov/pubmed/18566588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.117
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