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Early Fetal Gene Delivery Utilizes both Central and Peripheral Mechanisms of Tolerance Induction

(1) OBJECTIVE: We previously reported the induction of stable immune tolerance following the direct injection of retroviral vectors into preimmune fetal sheep. In the present studies, we conduct detailed analysis of the thymus of recipients of in utero gene transfer (IUGT) to delineate the mechanism...

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Detalhes bibliográficos
Main Authors: Colletti, Evan, Lindstedt, Sean, Park, Paul J., Almeida-Porada, Graça, Porada, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486147/
https://ncbi.nlm.nih.gov/pubmed/18400364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2008.02.007
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