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Chemical synthesis of the precursor molecule of the Aequorea green fluorescent protein, subsequent folding, and development of fluorescence

The present paper describes the total chemical synthesis of the precursor molecule of the Aequorea green fluorescent protein (GFP). The molecule is made up of 238 amino acid residues in a single polypeptide chain and is nonfluorescent. To carry out the synthesis, a procedure, first described in 1981...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nishiuchi, Yuji, Inui, Tatsuya, Nishio, Hideki, Bódi, József, Kimura, Terutoshi, Tsuji, Frederick I., Sakakibara, Shumpei
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24856/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.23.13549
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