Evidence of the in vivo esterification of budesonide in human airways

AIMS: Budesonide, unlike fluticasone propionate, undergoes fatty acid esterification in the lungs, and there is a need to characterize fully the distribution and fate of the two drugs after inhalation in humans. METHODS: This open-label, randomized study was performed in adults undergoing whole lung...

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Autori principali: van den Brink, Karen I Maassen, Boorsma, Martin, Staal-van den Brekel, Jeske A, Edsbäcker, Staffam, Wouters, Emiel F, Thorsson, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
Soggetti:
Pharmacodynamics and Pharmacokinetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485262/
https://ncbi.nlm.nih.gov/pubmed/18384442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03164.x
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