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Nasal retention of budesonide and fluticasone in man: Formation of airway mucosal budesonide-esters in vivo

AIMS: The efficacy of topical glucocorticosteroids in rhinitis and asthma is likely to depend on drug retention in the airway mucosa. With fluticasone propionate, retention may be achieved exclusively by lipophilicity, whereas for budesonide an additional possibility may be provided by its ability t...

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Hlavní autoři: Petersen, Hannes, Kullberg, Annika, Edsbäcker, Staffan, Greiff, Lennart
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014447/
https://ncbi.nlm.nih.gov/pubmed/11259988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2001.01303.x
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