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Nasal retention of budesonide and fluticasone in man: Formation of airway mucosal budesonide-esters in vivo

AIMS: The efficacy of topical glucocorticosteroids in rhinitis and asthma is likely to depend on drug retention in the airway mucosa. With fluticasone propionate, retention may be achieved exclusively by lipophilicity, whereas for budesonide an additional possibility may be provided by its ability t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Petersen, Hannes, Kullberg, Annika, Edsbäcker, Staffan, Greiff, Lennart
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014447/
https://ncbi.nlm.nih.gov/pubmed/11259988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2001.01303.x
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