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Bone sialoprotein binding to matrix metalloproteinase-2 alters enzyme inhibition kinetics

Bone sialoprotein (BSP) is a secreted glycophosphoprotein normally restricted in expression to skeletal tissue that is also induced by multiple neoplasms in vivo. Previous work has shown that BSP can bind to matrix metalloproteinase-2 (MMP-2). Because of MMP-2 activity in promoting tumor progression...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jain, Alka, Fisher, Larry W., Fedarko, Neal S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2484124/
https://ncbi.nlm.nih.gov/pubmed/18465841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800133n
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