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Immune response hinders therapy for lysosomal storage diseases
Enzyme replacement therapy (ERT) for the lysosomal storage disease mucopolysaccharidosis I (MPS I) involves i.v. injection of α-l-iduronidase, which can be taken up by cells throughout the body. While a significant immune response to ERT has been shown in patients with MPS I, little is known about w...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483689/ https://ncbi.nlm.nih.gov/pubmed/18654672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36521 |
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