Developing recombinant HPA-1a–specific antibodies with abrogated Fcγ receptor binding for the treatment of fetomaternal alloimmune thrombocytopenia

Fetomaternal alloimmune thrombocytopenia (FMAIT) is caused by maternal generation of antibodies specific for paternal platelet antigens and can lead to fetal intracranial hemorrhage. A SNP in the gene encoding integrin β3 causes a clinically important maternal-paternal antigenic difference; Leu33 ge...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ghevaert, Cedric, Wilcox, David A., Fang, Juan, Armour, Kathryn L., Clark, Mike R., Ouwehand, Willem H., Williamson, Lorna M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483683/
https://ncbi.nlm.nih.gov/pubmed/18654666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34708
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados