A Neuronal Glutamate Transporter Contributes to Neurotransmitter GABA Synthesis and Epilepsy

The predominant neuronal glutamate transporter, EAAC1 (for excitatory amino acid carrier-1), is localized to the dendrites and somata of many neurons. Rare presynaptic localization is restricted to GABA terminals. Because glutamate is a precursor for GABA synthesis, we hypothesized that EAAC1 may pl...

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Detalhes bibliográficos
Main Authors: Sepkuty, Jehuda P., Cohen, Akiva S., Eccles, Christine, Rafiq, Azhar, Behar, Kevin, Ganel, Raquelli, Coulter, Douglas A., Rothstein, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483507/
https://ncbi.nlm.nih.gov/pubmed/12151515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-15-06372.2002
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