Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling

INTRODUCTION: TNFα and high mobility group box chromosomal protein 1 (HMGB1) are two potent proinflammatory cytokines implicated as important mediators of arthritis. Increased levels of these cytokines are found in the joints of rheumatoid arthritis patients, and the cytokines trigger arthritis when...

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Autors principals: Pullerits, Rille, Jonsson, Ing-Marie, Kollias, George, Tarkowski, Andrej
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483464/
https://ncbi.nlm.nih.gov/pubmed/18582368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2445
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