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Disruption of Neuronal Autophagy by Infected Microglia Results in Neurodegeneration

There is compelling evidence to support the idea that autophagy has a protective function in neurons and its disruption results in neurodegenerative disorders. Neuronal damage is well-documented in the brains of HIV-infected individuals, and evidence of inflammation, oxidative stress, damage to syna...

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Detalhes bibliográficos
Main Authors: Alirezaei, Mehrdad, Kiosses, William B., Flynn, Claudia T., Brady, Nathan R., Fox, Howard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483417/
https://ncbi.nlm.nih.gov/pubmed/18682838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002906
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