Boc5, a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist, Invokes Sustained Glycemic Control and Weight Loss in Diabetic Mice

BACKGROUND: Our recent discovery of the substituted cyclobutane Boc5, one of the first non-peptidic agonists at glucagon-like peptide-1 receptors, offers the potential of combining oral availability with full agonism capable of eliciting antidiabetic and antiobesity effects. The present study was ai...

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Detalhes bibliográficos
Main Authors: Su, Haoran, He, Min, Li, Hongmei, Liu, Qing, Wang, Jia, Wang, Yiqian, Gao, Weiwei, Zhou, Ling, Liao, Jiayu, Young, Andrew A., Wang, Ming-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483413/
https://ncbi.nlm.nih.gov/pubmed/18682834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002892
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