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Therapeutic options in inflammatory bowel disease: experimental evidence of a beneficial effect of kinin B(1) receptor blockade

A surprising proportion of patients with inflammatory bowel disease (IBD) remain refractory to all classes of drugs presently in clinical use. Kinins are inflammatory mediators of potential relevance in IBD, because at least the kinin B(1) receptor subtype is upregulated in human or animal intestina...

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Detalhes bibliográficos
Main Authors: Marceau, F, Regoli, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483401/
https://ncbi.nlm.nih.gov/pubmed/18536746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.233
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