Auranofin promotes retinoic acid- or dihydroxyvitamin D(3)-mediated cell differentiation of promyelocytic leukaemia cells by increasing histone acetylation

BACKGROUND AND PURPOSE: To investigate the molecular mechanism for the effect of auranofin on the induction of cell differentiation, the cellular events associated with differentiation were analysed in acute promyelocytic leukaemia (APL) cells. EXPERIMENTAL APPROACH: The APL blasts from leukaemia pa...

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Main Authors: Park, S J, Kim, M, Kim, N H, Oh, M K, Cho, J K, Jin, J Y, Kim, I S
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2008
Ábhair:
Research Papers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483395/
https://ncbi.nlm.nih.gov/pubmed/18500361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.197
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