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Na(v)1.4 Deregulation in Dystrophic Skeletal Muscle Leads to Na(+) Overload and Enhanced Cell Death

Duchenne muscular dystrophy (DMD) is a hereditary degenerative disease manifested by the absence of dystrophin, a structural, cytoskeletal protein, leading to muscle degeneration and early death through respiratory and cardiac muscle failure. Whereas the rise of cytosolic Ca(2+) concentrations in mu...

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Autores principales: Hirn, Carole, Shapovalov, George, Petermann, Olivier, Roulet, Emmanuelle, Ruegg, Urs T.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483333/
https://ncbi.nlm.nih.gov/pubmed/18625851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810024
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