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Immune system derived from homeostatic proliferation generates normal CD8 T-cell memory but altered repertoires and diminished heterologous immune responses

The host responds to lymphopenic environments by acute homeostatic proliferation of T lymphocytes, which acquire phenotypes similar to memory cells. Using T-cell knockout (KO) mice adoptively reconstituted with splenocytes from immunologically naive mice, we examined the immune responses of an immun...

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Detalhes bibliográficos
Main Authors: Lin, Sue-Jane, Chen, Alex T., Welsh, Raymond M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481550/
https://ncbi.nlm.nih.gov/pubmed/18509089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-132464
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