Učitavanje...

Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification

CBFβ is the non-DNA binding subunit of the core binding factors (CBFs). Mice with reduced CBFβ levels display profound, early defects in T-cell but not B-cell development. Here we show that CBFβ is also required at very early stages of natural killer (NK)–cell development. We also demonstrate that T...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Guo, Yalin, Maillard, Ivan, Chakraborti, Sankhamala, Rothenberg, Ellen V., Speck, Nancy A.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481540/
https://ncbi.nlm.nih.gov/pubmed/18390836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-120261
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!