Synaptic Vesicles Are Constitutively Active Fusion Machines, Which Function Independently of Ca(2+)

BACKGROUND: In neurones, release of neurotransmitter occurs through the fusion of synaptic vesicles with the plasma membrane. Many proteins required for this process have been identified, with the SNAREs syntaxin 1, SNAP-25 and synaptobrevin thought to constitute the core fusion machinery. However,...

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Bibliographic Details
Main Authors:	Holt, Matthew, Riedel, Dietmar, Stein, Alexander, Schuette, Christina, Jahn, Reinhard
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2481520/ https://ncbi.nlm.nih.gov/pubmed/18485705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.04.069
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Synaptic Vesicles Are Constitutively Active Fusion Machines, Which Function Independently of Ca(2+)

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