RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

Parkinson's disease (PD) is a major neurodegenerative condition with several rare Mendelian forms. Oxidative stress and mitochondrial function have been implicated in the pathogenesis of PD but the molecular mechanisms involved in the degeneration of neurons remain unclear. DJ-1 mutations are o...

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Detalhes bibliográficos
Main Authors: van der Brug, Marcel P., Blackinton, Jeff, Chandran, Jayanth, Hao, Ling-Yang, Lal, Ashish, Mazan-Mamczarz, Krystyna, Martindale, Jennifer, Xie, Chengsong, Ahmad, Rili, Thomas, Kelly J., Beilina, Alexandra, Gibbs, J. Raphael, Ding, Jinhui, Myers, Amanda J., Zhan, Ming, Cai, Huaibin, Bonini, Nancy M., Gorospe, Myriam, Cookson, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481328/
https://ncbi.nlm.nih.gov/pubmed/18626009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708518105
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