Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis

BACKGROUND: Chromatin-associated histone H2AX is a key regulator of the cellular responses to DNA damage. However, non-nucleosomal functions of histone H2AX are poorly characterized. We have recently shown that soluble H2AX can trigger apoptosis but the mechanisms leading to non-chromatin-associated...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Liu, Ying, Parry, Joshua A, Chin, Anna, Duensing, Stefan, Duensing, Anette
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481267/
https://ncbi.nlm.nih.gov/pubmed/18616816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-61
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki