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Unveiling substrate RNA binding to H/ACA RNPs: one side fits all
The H/ACA RNP pseudouridylases function on a large number of extraordinarily complex RNA substrates including pre-ribosomal and small nuclear RNAs. Recent structural data show that H/ACA RNPs capture their RNA substrates via a simple one-sided attachment model. However, the precise placement of each...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2481233/ https://ncbi.nlm.nih.gov/pubmed/18178425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2007.11.004 |
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