DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma

The significance of chromosome 3p gene alterations in lung cancer is poorly understood. This study set out to investigate promoter methylation in the deleted in lung and oesophageal cancer 1 (DLEC1), MLH1 and other 3p genes in 239 non-small cell lung carcinomas (NSCLC). DLEC1 was methylated in 38.7%...

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Detalhes bibliográficos
Main Authors: Seng, T J, Currey, N, Cooper, W A, Lee, C-S, Chan, C, Horvath, L, Sutherland, R L, Kennedy, C, McCaughan, B, Kohonen-Corish, M R J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480971/
https://ncbi.nlm.nih.gov/pubmed/18594535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604452
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