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High Temperature Unfolding Simulations of the TRPZ1 Peptide

We report high temperature molecular dynamics simulations of the unfolding of the TRPZ1 peptide using an explicit model for the solvent. The system has been simulated for a total of 6 μs with 100-ns minimal continuous stretches of trajectory. The populated states along the simulations are identified...

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Detalhes bibliográficos
Main Authors: Settanni, Giovanni, Fersht, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480669/
https://ncbi.nlm.nih.gov/pubmed/18281384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.122606
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