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A General Test for Gene–Environment Interaction in Sib Pair-based Association Analysis of Quantitative Traits

Several association studies support the hypothesis that genetic variants can modify the influence of environmental factors on behavioral outcomes, i.e., G × E interaction. The case-control design used in these studies is powerful, but population stratification with respect to allele frequencies can...

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Detalhes bibliográficos
Main Authors: van der Sluis, Sophie, Dolan, Conor V., Neale, Michael C., Posthuma, Danielle
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480607/
https://ncbi.nlm.nih.gov/pubmed/18389355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10519-008-9201-8
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