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Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites

We describe the comprehensive characterization of homeodomain DNA-binding specificities from a metazoan genome. The analysis of all 84 independent homeodomains from D. melanogaster reveals the breadth of DNA sequences that can be specified by this recognition motif. The majority of these factors can...

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Bibliographische Detailangaben
Hauptverfasser: Noyes, Marcus B., Christensen, Ryan G., Wakabayashi, Atsuya, Stormo, Gary D., Brodsky, Michael H., Wolfe, Scot A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478728/
https://ncbi.nlm.nih.gov/pubmed/18585360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.05.023
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