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Lack of myristoylation of poliovirus capsid polypeptide VP0 prevents the formation of virions or results in the assembly of noninfectious virus particles.

We previously described the generation of a set of mutations into a cDNA of poliovirus type 1 in the myristoylation signal of the capsid polypeptide VP4 (D. Marc, G. Drugeon, A.-L. Haenni, M. Girard, and S. van der Werf, EMBO J. 8:2661, 1989). Genomic transcripts synthesized in vitro from the mutate...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Marc, D, Masson, G, Girard, M, van der Werf, S
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC247872/
https://ncbi.nlm.nih.gov/pubmed/2166807
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