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Characterization of poliovirus clones containing lethal and nonlethal mutations in the genome-linked protein VPg.

Viral RNA synthesis was assayed in HeLa cells transfected with nonviable poliovirus RNA mutated in the genome-linked protein VPg-coding region. The transfecting RNA was transcribed in vitro from full-length poliovirus type 1 (Mahoney) cDNA containing a VPg mutagenesis cartridge. Hybridization experi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Reuer, Q, Kuhn, R J, Wimmer, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2967-2975.1990
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