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Characterization of poliovirus clones containing lethal and nonlethal mutations in the genome-linked protein VPg.

Viral RNA synthesis was assayed in HeLa cells transfected with nonviable poliovirus RNA mutated in the genome-linked protein VPg-coding region. The transfecting RNA was transcribed in vitro from full-length poliovirus type 1 (Mahoney) cDNA containing a VPg mutagenesis cartridge. Hybridization experi...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Reuer, Q, Kuhn, R J, Wimmer, E
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.2967-2975.1990
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