The onset and extent of genomic instability in sporadic colorectal tumor progression

Cancer cell genomes contain alterations beyond known etiologic events, but their total number has been unknown at even the order of magnitude level. By sampling colorectal premalignant polyp and carcinoma cell genomes through use of the technique inter-(simple sequence repeat) PCR, we have found gen...

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Detalhes bibliográficos
Main Authors: Stoler, Daniel L., Chen, Neng, Basik, Mark, Kahlenberg, Morton S., Rodriguez-Bigas, Miguel A., Petrelli, Nicholas J., Anderson, Garth R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24783/
https://ncbi.nlm.nih.gov/pubmed/10611348
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