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Genomic Instability Measured by Inter-(Simple Sequence Repeat) PCR and High-Resolution Microsatellite Instability are Prognostic of Colorectal Carcinoma Survival After Surgical Resection

BACKGROUND: During the multiyear progression to colorectal cancer, numerous genomic alterations arise in events ranging from single base mutations to gains or losses of entire chromosomes. A single genetic change might not stand out as an independent predictor of outcome. The goal of this study was...

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Autores principales: Brenner, Bruce M., Swede, Helen, Jones, Beth A., Anderson, Garth R., Stoler, Daniel L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378325/
https://ncbi.nlm.nih.gov/pubmed/21487966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-011-1708-1
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