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Lack of Expression of Gp-130 Makes Pancreatic Beta Cell Lines Unresponsive to the IL-6 Family of Cytokines

Cytokine receptors from the IL-6 receptor family are comprised of ligand specific α chains and a common signalling chain, gp-130, which is also required for high affinity binding. A cDNA library generated from the β-TC3 SV40 T-antigen transformed insulinoma cell line was screened for members of this...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Naselli, Gaetano, Deaizpurua, Henry J., Thomas, Helen E., Johnston, Anne M., Kay, Thomas W. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2477742/
https://ncbi.nlm.nih.gov/pubmed/11467415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/EDR.2000.239
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