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Initial interaction of herpes simplex virus with cells is binding to heparan sulfate.

We have shown that cell surface heparan sulfate serves as the initial receptor for both serotypes of herpes simplex virus (HSV). We found that virions could bind to heparin, a related glycosaminoglycan, and that heparin blocked virus adsorption. Agents known to bind to cell surface heparan sulfate b...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: WuDunn, D, Spear, P G
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2535752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.1.52-58.1989
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