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Initial interaction of herpes simplex virus with cells is binding to heparan sulfate.

We have shown that cell surface heparan sulfate serves as the initial receptor for both serotypes of herpes simplex virus (HSV). We found that virions could bind to heparin, a related glycosaminoglycan, and that heparin blocked virus adsorption. Agents known to bind to cell surface heparan sulfate b...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: WuDunn, D, Spear, P G
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2535752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.1.52-58.1989
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