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Genetic and Physiological Aspects of Resistance to 5-Fluoropyrimidines in Saccharomyces cerevisiae

Mutants resistant to 5-fluorouracil, 5-fluorocytosine, and 5-fluorouridine were selected in yeast, and the mechanisms of their resistance were investigated. The investigated mutations map in seven different loci. (i) A mutation at the locus FUI 1 gives specifically resistance to 5-fluorouridine. (ii...

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Bibliografske podrobnosti
izdano v:J Bacteriol
Main Authors: Jund, Richard, Lacroute, François
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1970
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247602/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5429721/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.102.3.607-615.1970
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