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Genetic and Physiological Aspects of Resistance to 5-Fluoropyrimidines in Saccharomyces cerevisiae

Mutants resistant to 5-fluorouracil, 5-fluorocytosine, and 5-fluorouridine were selected in yeast, and the mechanisms of their resistance were investigated. The investigated mutations map in seven different loci. (i) A mutation at the locus FUI 1 gives specifically resistance to 5-fluorouridine. (ii...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Jund, Richard, Lacroute, François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247602/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5429721/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.102.3.607-615.1970
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