Selective Loss of Podoplanin Protein Expression Accompanies Proteinuria and Precedes Alterations in Podocyte Morphology in a Spontaneous Proteinuric Rat Model

To evaluate changes during the development of proteinuria, podocyte morphology and protein expression were evaluated in spontaneously proteinuric, Dahl salt-sensitive (Dahl SS) rats. Dahl SS rats on a low-salt diet were compared with spontaneously hypertensive rats (SHR) at age 2, 4, 6, 8, and 10 we...

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Hauptverfasser: Koop, Klaas, Eikmans, Michael, Wehland, Markus, Baelde, Hans, Ijpelaar, Daphne, Kreutz, Reinhold, Kawachi, Hiroshi, Kerjaschki, Dontscho, de Heer, Emile, Bruijn, Jan Anthonie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475770/
https://ncbi.nlm.nih.gov/pubmed/18599604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080063
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