Allostery in Recombinant Soluble Guanylyl Cyclase from Manduca sexta

Soluble guanylyl/guanylate cyclase (sGC), the primary biological receptor for nitric oxide, is required for proper development and health in all animals. We have expressed heterodimeric full-length and N-terminal fragments of Manduca sexta sGC in Escherichia coli, the first time this has been accomp...

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Bibliographic Details
Main Authors: Hu, Xiaohui, Murata, Lauren B., Weichsel, Andrzej, Brailey, Jacqueline L., Roberts, Sue A., Nighorn, Alan, Montfort, William R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Enzyme Catalysis and Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475682/
https://ncbi.nlm.nih.gov/pubmed/18515359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801501200
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