Cytosine ribose flexibility in DNA: a combined NMR (13)C spin relaxation and molecular dynamics simulation study

Using (13)C spin relaxation NMR in combination with molecular dynamic (MD) simulations, we characterized internal motions within double-stranded DNA on the pico- to nano-second time scale. We found that the C–H vectors in all cytosine ribose moieties within the Dickerson–Drew dodecamer (5′-CGCGAATTC...

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Bibliografiske detaljer
Main Authors: Duchardt, Elke, Nilsson, Lennart, Schleucher, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2008
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475628/
https://ncbi.nlm.nih.gov/pubmed/18579564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn375
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