Mitochondrial Dysfunction Increases Oxidative Stress and Decreases Chronological Life Span in Fission Yeast

BACKGROUND: Oxidative stress is a probable cause of aging and associated diseases. Reactive oxygen species (ROS) originate mainly from endogenous sources, namely the mitochondria. METHODOLOGY/PRINCIPAL FINDINGS: We analyzed the effect of aerobic metabolism on oxidative damage in Schizosaccharomyces...

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Hlavní autoři: Zuin, Alice, Gabrielli, Natalia, Calvo, Isabel A., García-Santamarina, Sarela, Hoe, Kwang-Lae, Kim, Dong Uk, Park, Han-Oh, Hayles, Jacqueline, Ayté, José, Hidalgo, Elena
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475502/
https://ncbi.nlm.nih.gov/pubmed/18665268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002842
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