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Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces

Members of the soil-dwelling prokaryotic genus Streptomyces produce many secondary metabolites, including antibiotics and anti-tumour agents. Their formation is coupled with the onset of development, which is triggered by the nutrient status of the habitat. We propose the first complete signalling c...

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Detalhes bibliográficos
Main Authors: Rigali, Sébastien, Titgemeyer, Fritz, Barends, Sharief, Mulder, Suzanne, Thomae, Andreas W, Hopwood, David A, van Wezel, Gilles P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475330/
https://ncbi.nlm.nih.gov/pubmed/18511939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.83
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