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Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival

Bcl-2, which can both reduce apoptosis and retard cell cycle entry, is thought to have important roles in hematopoiesis. To evaluate the impact of its ubiquitous overexpression within this system, we targeted expression of the human bcl-2 gene in mice by using the promoter of the vav gene, which is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ogilvy, Sarah, Metcalf, Donald, Print, Cristin G., Bath, Mary L., Harris, Alan W., Adams, Jerry M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC24752/
https://ncbi.nlm.nih.gov/pubmed/10611317
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