Correlation Between Hydrolysis of the β-Lactam Bond of the Cephalosporin Nucleus and Expulsion of the 3-Substituent
The hydrolysis of two cephalosporins by three different β-lactamases has been studied. Each enzyme caused a decrease in ultraviolet absorption, a loss of biological activity, and the release of the leaving group from the 3-position. The changes occurred at the same rate and to the same extent with e...
Uloženo v:
| Vydáno v: | J Bacteriol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1972
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247519/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4555421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.110.3.988-991.1972 |
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