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Effect of the Folic Acid Analogue, Trimethoprim, on Growth, Macromolecular Synthesis, and Incorporation of Exogenous Thymine in Escherichia coli

The effect of trimethoprim [2,4-diamino-5(2′,4′,5′trimethoxybenzyl)-pyrimidine] in the presence of thymine on Escherichia coli B temperature-sensitive and non-temperature-sensitive Thy(′) strains and a phosphodeoxyribomutase-negative mutant was studied. The inhibitory effect of 5 μg of trimethoprim...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Dale, Beverly A., Greenberg, G. Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1972
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247509/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4260561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.110.3.905-916.1972
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